Registered Nurse Salary in Mississippi

How Much Does a Registered Nurse Make in Mississippi?

The typical Registered Nurse salary in Mississippi ranges from $53,900 to $100,100, with the national median at $77,000.

Provide patient care, educate patients, and provide emotional support Your actual take-home pay as a Registered Nurse in Mississippi depends on:

• Your specific salary or hourly rate
• Federal income tax (10% to 37% progressive rates)
• FICA taxes (7.65% for Social Security and Medicare)
• Mississippi state income tax
• Local taxes (if applicable in your city)
• Health insurance and retirement contributions
• Cost of living in your specific city or region

Taxes for Registered Nurse in Mississippi

As a Registered Nurse working in Mississippi, you'll pay the following taxes on your income:

Federal Income Tax

Everyone in the US pays federal income tax, including Registered Nurse professionals. The federal tax system uses progressive tax brackets ranging from 10% to 37%, meaning you pay different rates on different portions of your income.

FICA Taxes

Social Security and Medicare taxes (FICA) total 7.65% of your gross income:

• Social Security: 6.2% (on first $168,600 in 2025)
• Medicare: 1.45% (no income limit)
• Additional Medicare: 0.9% on income over $200,000

Mississippi State Income Tax

Mississippi has a state income tax that applies to all Registered Nurse salaries earned in the state. The exact rate depends on Mississippi's tax brackets and your total income.

Use our Mississippi salary calculator to see your exact state tax based on your Registered Nurse salary.

Cost of Living for Registered Nurse in Mississippi

Your Registered Nurse salary goes further or shorter depending on the cost of living in your area of Mississippi. Key factors include:

• Housing: Rent or mortgage payments (often 25-35% of take-home pay)
• Transportation: Car payments, gas, insurance, or public transit
• Food: Groceries and dining out
• Healthcare: Insurance premiums, copays, prescriptions
• Utilities: Electric, gas, water, internet

A $77,000 Registered Nurse salary in a low-cost area of Mississippi provides significantly more buying power than the same salary in an expensive metro area.

Registered Nurse Salary Examples in Mississippi

Here's what different Registered Nurse salary levels look like in Mississippi:

Entry-Level Registered Nurse ($53,900)

• Gross annual salary: $53,900
• Federal tax: ~$6,468
• FICA: ~$4,123
• Mississippi state tax: Varies
• Approximate take-home: $37,730

Median Registered Nurse ($77,000)

• Gross annual salary: $77,000
• Federal tax: ~$12,320
• FICA: ~$5,891
• Mississippi state tax: Varies
• Approximate take-home: $51,590

Experienced Registered Nurse ($100,100)

• Gross annual salary: $100,100
• Federal tax: ~$22,022
• FICA: ~$7,658
• Mississippi state tax: Varies
• Approximate take-home: $60,060

Calculate your exact take-home pay: These are estimates. For precise calculations based on your specific situation, use our Mississippi salary calculator.

Compare Registered Nurse Salaries Across States

The same Registered Nurse salary can result in very different take-home pay depending on the state:

• No-tax states (TX, FL, NV, TN, WA): Higher take-home pay
• Low-tax states (AZ, IN, ND, PA): Moderate take-home pay
• High-tax states (CA, NY, NJ, HI): Lower take-home pay

A $77,000 Registered Nurse salary in California results in about $3,850 to $7,700 less take-home pay per year compared to the same salary in a no-tax state.

Frequently Asked Questions

What is the average Registered Nurse salary in Mississippi?

The average Registered Nurse salary in Mississippi varies by experience, location within the state, and employer. The national median is $77,000, with typical Mississippi salaries ranging from $53,900 to $100,100.

How much does a Registered Nurse make after taxes in Mississippi?

After federal taxes, FICA, Mississippi state tax, and typical deductions, a Registered Nurse earning $77,000 in Mississippi takes home approximately $50,050 to $53,900 per year.

Is Mississippi a good state for Registered Nurse professionals?

It depends on your priorities. Consider Mississippi's cost of living, career opportunities, quality of life, and state tax burden when evaluating your options.

Next Steps

Ready to see your exact Registered Nurse take-home pay in Mississippi?

Use our Mississippi salary calculator →

Or compare Registered Nurse salaries across different states to find the best location for your career.